Awardees' Articles

HFSP Long-Term Fellow Benyamin Rosental and colleagues

Friday 7th December 2018

Through functional and molecular characterization on the cellular level of a colonial chordate animal we have found the evolutionary origins of our own immune and the blood-forming systems.

 

HFSP Cross-Disciplinary Fellow Pietro Artoni and colleagues

Tuesday 4th December 2018

High-density Electroencephalography (EEG) and single-neuron calcium imaging are two complementary techniques for studying brain computation in vivo, enabling the electric waves on the brain surface and the neuronal code of the biological networks that originate the waves to be measured. By nanofabricating dense and transparent multi-electrode arrays, EEG and single-neuron calcium activity can be simultaneously measured in the mouse visual cortex, providing a new tool to better understand cortical...

 

HFSP Long-Term Fellow Raya Sorkin and colleagues

Thursday 15th November 2018

Mechanical properties of cells are important reporters of a cell's condition, as they often change upon disease. We have developed a new approach to measure mechanical properties of cells using acoustically exerted forces. This method allowed us to reveal that red blood cells become more deformable when they uptake extracellular vesicles.

 

HFSP Program Grant holder David Lambert and colleagues

Thursday 8th November 2018

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HFSP Career Development Award holder Patrick Mueller and colleagues

Tuesday 16th October 2018

During embryo development, two molecules adjust tissue proportions to the size of the embryo.

 

HFSP Career Development Award holder Andrea Pauli and colleagues

Monday 15th October 2018

Research in the Pauli lab has discovered a new protein that is essential for species-specific fertilization in fish. The story was recently published in Science.

 

HFSP Program Grant holders Melissa Little and Ian Smyth and colleagues

Monday 8th October 2018

Branching morphogenesis is an ancient process integral to the development of many organs; however, the extent to which it shares features between organs is unclear. We found distinct differences in how the kidney and the mammary gland elaborate, which do not support previous claims for the existence of a unifying theory of branching morphogenesis.

 

HFSP Program Grant holder Maria Garcia-Parajo and colleagues

Thursday 4th October 2018

A new microscopy approach for simultaneous multicolour imaging with single molecule sensitivity has been developed in the Garcia-Parajo lab.

 

HFSP Long-Term Fellow Omer Ziv and colleagues

Monday 1st October 2018

RNA viruses use multiple strategies to enhance the functional capacity of their small genomes. This study reports on a new technique to determine the structure of viral RNA genomes while replicating inside human cells and to explore how viruses interact with the host's own RNA. It reveals the dynamic nature of the Zika virus genome and enables new strategies to interfere with the virus infectious cycle to be designed.

 

HFSP Program Grant holder Kenneth Welch and colleagues

Friday 28th September 2018

Unlike most vertebrates, hummingbird flight muscle expresses transcripts that encode proteins that enable high transport and oxidation capacity for not just glucose, but fructose as well. This suggests the cellular physiology of hummingbird muscles is specialized to efficiently extract energy from their unusual fructose-rich diet.