Awardees' Articles

HFSP Long-Term Fellow Pavan Ramdya and colleagues

Tuesday 1st December 2015

The brain is never quiet. Activity fluctuations - or noise - impinge upon all neural circuits and may therefore have an important effect on decision-making. A former HFSP Long-Term Fellow, Pavan Ramdya, and colleagues explored this possibility by generating and studying noise-driven artificial neural networks that are able to mimic the unpredictable timing of fruit fly walking behaviors.

 

HFSP Long-Term Fellow Einat Segev and colleagues

Monday 30th November 2015

Roseobacters are a group of marine bacteria that interact with many different hosts in the ocean. Various Roseobacters are capable of physically attaching to their hosts, to each other and to various surfaces. A key question is how do these bacteria attach?

 

HFSP Long-Term Fellow Eirini Kaiserli and colleagues

Friday 27th November 2015

Flowering is controlled by multiple environmental stimuli. A new signal-integrating component of light and photoperiodic signalling is recruited to nuclear photobodies to regulate the transcriptional activation of flowering time in Arabidopsis thaliana.

 

HFSP Long-Term Fellow Iain Mathieson and colleagues

Thursday 26th November 2015

Ancient DNA makes it possible to observe natural selection directly by looking for parts of the genome that changed rapidly over time. By sequencing the genomes of ancient Europeans who lived during the past eight thousand years, we find selection on genes associated with diet, pigmentation and immunity, likely driven by the transition to an agricultural lifestyle in new environments at this time.

 

HFSP Cross-Disciplinary Fellow Kurt Schmoller and HFSP Long-Term Fellow Mardo Kõivomägi and colleagues

Tuesday 24th November 2015

Many cells, including the unicellular organism budding yeast, control their own size by linking growth and division. Now, a molecular mechanism that allows budding yeast to measure and adjust its own size has been identified.

 

HFSP Young Investigator Grant holder Rosalind Allen and colleagues

Monday 23rd November 2015

We have tracked how bacteria compete for space when they grow on a surface, using a microscope and computer simulations. The "winners" of this ecological competition depend on both the speed at which bacteria colonize the space around them and the interactions between competing populations when they collide.

 

HFSP Program Grant holder David Lentink and colleagues

Friday 20th November 2015

HFSP Program Grant awardee David Lentink and his colleagues have developed a novel suspension system for in-flight cameras using whooper swan flight as a cue for their latest tech tool. The development of this new tool is an essential element in an HFSP funded collaboration with colleagues in Australia and Canada to understand the exquisite flight control mechanisms of birds because they exhibit complex and diverse flight, and naturally fly over regions typically not easily accessible to controlled...

 

HFSP Long-Term Fellow Caspar Schwiedrzik and HFSP Program Grant holder Winrich Freiwald and colleagues

Thursday 19th November 2015

Studying the connectivity of face processing areas in monkeys reveals the routes by which information about faces is exchanged with other brain areas supporting socially, emotionally, and cognitively relevant functions, and uncovers a set of brain areas stunningly similar to the network implementing high-level social cognition in humans.

 

HFSP Career Development Award holder Pablo Manavella and colleagues

Tuesday 17th November 2015

MicroRNAs (miRNAs) are key regulators of plant development. These small molecules are produced by a dynamic but highly coordinated process. The processing of miRNA is carried out by a group of well-characterized proteins. Despite the handful of cofactors regulating this process that have been identified in recent years, it is unclear how the plant fine-tunes the production of miRNA in different tissues. Now, RCF3 was identified as a regulator of the miRNA processing machinery acting preferentially...

 

HFSP Long-Term Fellow Yonatan Stelzer and colleagues

Monday 16th November 2015

DNA methylation is considered a key epigenetic modification that shapes and maintains cellular identity. In recent years, advancements in sequencing technologies enabled the generation of detailed single-base resolution maps of DNA methylation in multiple cell types. However, current methods only provide a static "snapshot" of the methylation levels thus precluding the study of real-time epigenetic changes and limiting prospective mechanistic experiments. Here, we established a novel reporter...