Awardees' Articles

HFSP Young Investigator Grant holder William Ryu and colleagues

Monday 6th February 2017

Although the nematode C. elegans has a simple nervous system, it has a complex response to changes in temperature. For small changes in temperature, such as the worm experiences when moving in a shallow thermal gradient, the worm can perform thermotaxis and migrate to a temperature that it prefers. However, if the temperature changes are very fast or very large, the worm will respond noxiously and attempt to escape the stimulus. The neurons and their signals that control these behaviors have not...

 

HFSP Long-Term Fellow Einat Segev and colleagues

Friday 3rd February 2017

Microscopic algae that live in the ocean release countless tons of oxygen into the atmosphere each year. Widespread algae - known as coccolithophores - surround their little plant-like body with a mineral shell made of a material similar to chalk. These microscopic algae form seasonal blooms. Over several weeks in early summer, the algae grow to enormous numbers and cover hundreds of thousands of square kilometers in the ocean. These blooms become so vast that satellites can detect them. However...

 

HFSP Program Grant holders Daniel Wolpert and Michael Shadlen and colleagues

Thursday 2nd February 2017

In tasks that require a number of decisions to achieve a goal, confidence in one decision affects the way the brain chooses to make the subsequent decision.

 

HFSP Long-Term Fellow William Durham and colleagues

Monday 30th January 2017

Most of what we know about microbial communities comes from studying cells in the laboratory as they grow in liquid culture. In these well-mixed conditions, evolution selects for the species that can reproduce the fastest. However, more than 95% of the bacteria on Earth live in complex porous environments like soil where they form surface attached biofilms.

 

HFSP Career Development Award holder Pedro Beltrao and colleagues

Friday 27th January 2017

Kinase-driven signalling is crucial for the coordinated adjustment of cellular changes and cell decision making. However, measuring the changes of activity for a large number of kinases remains a difficult challenge. Ochoa et al. inferred, from publicly available mass spectrometry data, the kinase regulation of 215 kinases under 399 different perturbations, allowing for a systematic study of the fundamental rules governing cellular signalling.

 

HFSP Young Investigator Grant holder Flavio Frohlich and colleagues

Thursday 26th January 2017

Anatomically and functionally connected brain regions form networks that collectively give rise to sensory, motor, and cognitive functions. Dr. Frohlich and his team revealed that the ferret brain exhibits such networks including the default mode network, which has been implicated in human psychiatric disorder.

 

HFSP Cross-Disciplinary Fellow Fernando Montealegre-Z and colleagues

Tuesday 24th January 2017

An acute and advanced hearing system which allows bush-crickets to listen to the same sound twice with the same ear - enabling them to locate the sound's origin with pinpoint accuracy - has been demonstrated by scientists at the Universities of Lincoln and Bristol, UK.

 

HFSP Program Grant holder Mandyam Srinivasan and colleagues

Monday 23rd January 2017

High-speed video films of budgerigars flying through a tapered corridor reveal that these birds tend to fly at two distinct speeds: a high speed (approximately 10 m/s) for cruising in open environments, and a low speed (approximately 5 m/s) for maneuvering in cluttered environments [1].

 

HFSP Young Investigator Grant holder Kristian Franze and colleagues

Thursday 19th January 2017

For decades it was assumed that growing neurons find their way through the developing brain using chemical signals only. However, it turns out that neurons also 'feel' the stiffness of the tissue and that this is equally important for proper outgrowth.

 

HFSP Young Investigator Grant holder Gang Han and colleagues

Tuesday 17th January 2017

HFSP grant holder Gang Han and his team have designed a highly NIR-sensitive organic nanoparticle that is able to be operated with cost-effective low power lamp light to kill cancer tumors in deep tissue.