HFSP success stories

Featuring studies conducted by HFSP Awardees, both past and present. See also ...

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How many protein molecules do we have in our cells?

Images from the Vogel lab

Proteins are crucial to the structure and function of living cells. Great effort is now being applied to understanding cells at a systemic level and knowledge of the proteins and their interactions are critical to understanding the integrative functions of biological systems. Former HFSP Long-Term Fellow, Christine Vogel, has developed important experimental and theoretical approaches to investigating the myriads of proteins in the cell. Following a productive and successful period in the...

Water and biological molecules probed by Terahertz spectroscopy

Dynamical hydration layer around a protein

Water is a major constituent of living cells but cellular constituents such as proteins are so tightly packed that the space available for water is limited. To investigate water at the interface  and its interactions with biomolecules, Martina Havenith, with colleagues Martin Gruebele and David Leitner, applied to HFSP to fund a project to use the new method of Terahertz spectroscopy as a probe for water-biomolecule interaction. This Germany-USA collaboration was considered very high-...