HFSP success stories

Featuring studies conducted by HFSP Awardees, both past and present. See also ...

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Looking back on the launch of single molecule biophysics

HFSP and the beginnings of single molecule biophysics

Molecular motors play a key role in controlling movement in living cells. A well-known example is myosin, originally described as a key player in muscle contraction, but which is involved in many cell biological phenomena. Detailed knowledge of the function of myosin and its interaction with its partner molecule, actin has been obtained in recent years by studying single molecules of these important proteins. Here, James Spudich of Stanford University looks back to the time when he and his...