Guiding light: the mysteries of firefly bioluminescence unfold

In 2011, HFSP awarded a Young Investigator Grant to an international team of researchers to study the "Excited-State Structure of the Emitter and Color-Tuning Mechanism of the Firefly Bioluminescence".  The findings of this successful four-way collaboration between the labs of Pance Naumov (Japan/Abu Dhabi), Pascal Didier (France), Lukas Hintermann (Germany) and Michel Sliwa (France) are described in the following article by Pance Naumov, Principal Inves

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By HFSP Young Investigator Grant holder Pance Naumov
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HFSP Matters - May 2014


Dear Colleague,

Happenchance and hedgehogs

Earlier this year, the European Medicines Agency approved the use of a new anti-cancer drug, Erivedge, developed by Genentech in collaboration with the Cambridge (Mass) based biotech company Curis Inc, for the treatment of Basal Cell Carcinoma (BCC), the most common cancer amongst Caucasians. This decision followed similar approval for its clinical use in the USA by the FDA in 2012.

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By HFSP alumnus Philip Ingham
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HFSP Matters - November 2013

Crowdsourcing the design of swarming nanoparticles for cancer applications

The treatment of cancer is undergoing what could be called a revolution. The field has attracted the attention of bioengineers trying to design nanoparticles that can deliver drugs and therapeutics directly to tumors. Their size, typically 10 nm to 500 nm, is ideal to leak out of porous vessels deep in tumors while remaining in the blood stream throughout the rest of the body.

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Frontier science matters
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by HFSP Cross-Disciplinary Fellow Sabine Hauert
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Insect jumping, an ancient question

The acrobatic leaps of insects have fascinated both storytellers and scientists for the scope of human history.  Aristophanes wrote in amazement about how far fleas could jump [Ref. 1], suggesting that their jump distance be measured in ‘flea feet’, and compared to the ‘human feet’ of man’s leaps.  Hans Christian Anderson likewise marvelled at jumping insects, writing a cautionary tale of a contest between a flea, a grasshopper, and a tuna.

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Frontier science matters
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By former HFSP Cross-Disciplinary Fellow Gregory Sutton
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OpenSPIM: an open access light sheet microscopy platform

Light sheet microscopy is an emerging technique that allows developmental and cell biologists to record entire living systems with minimal photo-damage over extended periods of time. The technology has thus far been applied to produce spectacular proof of principle recordings of model organism embryos which capture the developing specimen at cellular resolution throughout early development.

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HFSP success stories
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OpenSPIM: an open access light sheet microscopy platform
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HFSP Matters - September 2013


Dear Colleague,

HFSP News - 16 December 2011

In this issue:

1. Information and guidelines for 2013 Research Grants are now available
2. Major Prizes for HFSP Alumni
3. New Newsletter coming in 2012

4. Keep up with news about HFSP
5. Impressum and Subscription info

How many protein molecules do we have in our cells?

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HFSP success stories
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Images from the Vogel lab
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