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Decoding the function of expansion segments in ribosomes

Eukaryote specific expansion segments (ESs) in the rRNA increase fidelity of mRNA translation. ESs are enigmatic…

Ojosnegros2019b

A novel imaging technique reveals protein dynamics in live cells

Proteins continuously interact with other proteins in the cell, yet revealing these interactions in live-cell…

Gould2019a

The talin code – a cellular code that enables cells to use the force

It is becoming evident that cells interpret classical signaling pathways in the context of the mechanical forces…

Restoring axonal regeneration in neurodegenerative diseases

Several neurodegenerative conditions including most instances of amyotrophic lateral sclerosis and frontotemporal…

The cell source of scar tissues that binds organs to one another after abdominal surgery is identified and can be targetable

Adhesions are fibrous bands that glue organ surfaces with one another or with the walls of the cavity they reside in…

Uncovering mechanisms of centrosome biogenesis and targeting them in cancer cells

In contrast to normal cells, cancer cells harbor extra centrosomes and centrosome amplification is a hallmark of cancer…

Meercats

Meerkats take turns while calling in groups

Turn-taking is a basic feature of human communication, but other animals also take turns. During group calling sessions…

Mathijssen 2018b

Microbial carpets generate vortex flows to attract nutrients

How do bacteria gather nutrients when they cluster in dense colonies? HFSP fellow Arnold Mathijssen discovered that…

A tunicate immune system reveals how similar we are

Through functional and molecular characterization on the cellular level of a colonial chordate animal we have found the…

Transparent electrodes for coupling imaging and electrophysiology in the brain

High-density Electroencephalography (EEG) and single-neuron calcium imaging are two complementary techniques for…

Using sound to stretch cells

Mechanical properties of cells are important reporters of a cell's condition, as they often change upon disease. We…

The first evolution debate and ancient Egyptian mummies

Fifty years before Darwin's "On the Origin of Species" was published, the first test of evolution had already been…