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 Descartes’ classic drawing on the reflex arc of pain (from L’Homme, 1662)

Warm on a cold night: the neurological basis of behavioral thermoregulation

Thermoregulatory behavior is a basic motivated behavior for body temperature homeostasis. Despite its critical…

Overview of protein machine assembly

Computational design of the first synthetic protein rotary machines

Using cutting-edge computational methods and cryoelectron microscopy, we designed synthetic protein components that…

Distant genes pair together

Genomically apart, but acting together: gene coupling in living embryos

Genes can be tightly co-regulated despite large genomic separation. In developing fly embryos, shared enhancers co…

Jackdaws in winter roosts

Jackdaws use a vocal voting system to make consensus decisions

Roosting jackdaws call to reach a consensus to depart together. Using field recordings and playback experiments, Alex…

 Illustration of the ScanNet model

Mapping antibody epitopes onto protein structures with deep learning

Following immunization against a protein antigen, our body matures antibodies that specifically bind the antigen. But…

African penguins

Water or land: are the middle ears of aquatic birds designed to hear in both?

For highly aquatic birds, hearing underwater might be as important as hearing on land. Yet, specializations to hearing…

Confocal microscopy image of the developing fly optic lobe

How stem cells generate neuronal diversity over time

The molecular players that pattern neural stem cells to generate neuronal diversity as the brain develops are mostly…

A sense for number in the zebrafish brain

A sense for number in the zebrafish brain

Neurons in a restricted region of the zebrafish brain show selective activation upon change in the number of items in a…

Pseudomonas cells surrounding a stoma of an A. thaliana plan

The microbial enemy of my enemy is my friend

For plants, microbial pathogens are a fact of life, yet most plants do not succumb to disease. Surrounding beneficial…

Representation of the multisynthetase complex in a human cell

These ancient enzymes like to stick together – but why?

Aminoacyl-tRNA synthetases are the enzymes that know the genetic code – they connect transfer RNA (tRNA) adapters to…

In vitro ribosome assembly with recombinant proteins

In vitro ribosome assembly with recombinant proteins

Functional in vitro assembly of the Escherichia coli ribosome was demonstrated with 54 recombinantly prepared ribosomal…

Simulation of bipolar spindle formation

Flowing by gelating

The segregation of chromosomes during cell division is an intricate process involving the assembly of the mitotic…